Non-muscular myosin light chain kinase triggers intermittent hypoxia-induced interleukin-6 release, endothelial dysfunction and permeability

Obstructive sleep apnea is characterized by intermittent hypoxia (IH) which alters endothelial function, induces inflammation and accelerates atherosclerosis-induced cardiovascular diseases. The non-muscular myosin light chain kinase (nmMLCK) isoform contributes to endothelial cell-cell junction ope...

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Vydáno v:Sci Rep
Hlavní autoři: Recoquillon, Sylvain, Gómez-Guzmán, Manuel, Rodier, Marion, Koffi, Camille, Nitiéma, Mathieu, Gagnadoux, Frédéric, Martínez, M. Carmen, Andriantsitohaina, Ramaroson
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651916/
https://ncbi.nlm.nih.gov/pubmed/29057883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13268-5
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