Pre-fusion RSV F strongly boosts pre-fusion specific neutralizing responses in cattle pre-exposed to bovine RSV

Human respiratory syncytial virus (hRSV) is responsible for serious lower respiratory tract disease in infants and in older adults, and remains an important vaccine need. RSV fusion (F) glycoprotein is a key target for neutralizing antibodies. RSV F stabilized in its pre-fusion conformation (DS-Cav1...

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Publicado no:Nat Commun
Main Authors: Steff, Ann-Muriel, Monroe, James, Friedrich, Kristian, Chandramouli, Sumana, Nguyen, Thi Lien-Anh, Tian, Sai, Vandepaer, Sarah, Toussaint, Jean-François, Carfi, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651886/
https://ncbi.nlm.nih.gov/pubmed/29057917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01092-4
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