Pannexin1 links lymphatic function to lipid metabolism and atherosclerosis

Extracellular ATP is a central signaling molecule in inflammatory responses. Pannexin1 (Panx1) channels release ATP in a controlled manner and have been implicated in various inflammatory pathologies, but their role in atherogenesis remains elusive. Using atherosclerosis-susceptible mouse models wit...

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Udgivet i:Sci Rep
Main Authors: Molica, Filippo, Meens, Merlijn J., Dubrot, Juan, Ehrlich, Avigail, Roth, Christel L., Morel, Sandrine, Pelli, Graziano, Vinet, Laurent, Braunersreuther, Vincent, Ratib, Osman, Chanson, Marc, Hugues, Stephanie, Scemes, Eliana, Kwak, Brenda R.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651868/
https://ncbi.nlm.nih.gov/pubmed/29057961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14130-4
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