A New Generation of Arachidonic Acid Analogues as Potential Neurological Agent Targeting Cytosolic Phospholipase A(2)

Cytosolic phospholipase A(2) (cPLA(2)) is an enzyme that releases arachidonic acid (AA) for the synthesis of eicosanoids and lysophospholipids which play critical roles in the initiation and modulation of oxidative stress and neuroinflammation. In the central nervous system, cPLA(2) activation is im...

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Publicado no:Sci Rep
Main Authors: Ng, Cheng Yang, Kannan, Srinivasaraghavan, Chen, Yong Jun, Tan, Francis Chee Kuan, Ong, Wee Yong, Go, Mei Lin, Verma, Chandra S., Low, Chian-Ming, Lam, Yulin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651845/
https://ncbi.nlm.nih.gov/pubmed/29057981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13996-8
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