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Structure and dynamics of the RNAPII CTDsome with Rtt103

RNA polymerase II contains a long C-terminal domain (CTD) that regulates interactions at the site of transcription. The CTD architecture remains poorly understood due to its low sequence complexity, dynamic phosphorylation patterns, and structural variability. We used integrative structural biology...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Jasnovidova, Olga, Klumpler, Tomas, Kubicek, Karel, Kalynych, Sergei, Plevka, Pavel, Stefl, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651779/
https://ncbi.nlm.nih.gov/pubmed/29073019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712450114
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