Discovery of an O-mannosylation pathway selectively serving cadherins and protocadherins

The cadherin (cdh) superfamily of adhesion molecules carry O-linked mannose (O-Man) glycans at highly conserved sites localized to specific β-strands of their extracellular cdh (EC) domains. These O-Man glycans do not appear to be elongated like O-Man glycans found on α-dystroglycan (α-DG), and we r...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Larsen, Ida Signe Bohse, Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Siukstaite, Lina, Harrison, Oliver J., Brasch, Julia, Goodman, Kerry M., Hansen, Lars, Shapiro, Lawrence, Honig, Barry, Vakhrushev, Sergey Y., Clausen, Henrik, Halim, Adnan
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651762/
https://ncbi.nlm.nih.gov/pubmed/28973932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708319114
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