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Minimal and RNA-free RNase P in Aquifex aeolicus

RNase P is an essential tRNA-processing enzyme in all domains of life. We identified an unknown type of protein-only RNase P in the hyperthermophilic bacterium Aquifex aeolicus: Without an RNA subunit and the smallest of its kind, the 23-kDa polypeptide comprises a metallonuclease domain only. The p...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Nickel, Astrid I., Wäber, Nadine B., Gößringer, Markus, Lechner, Marcus, Linne, Uwe, Toth, Ursula, Rossmanith, Walter, Hartmann, Roland K.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651759/
https://ncbi.nlm.nih.gov/pubmed/29073018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707862114
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