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Spontaneous Mutation at Amino Acid 544 of the Ebola Virus Glycoprotein Potentiates Virus Entry and Selection in Tissue Culture
Ebolaviruses have a surface glycoprotein (GP(1,2)) that is required for virus attachment and entry into cells. Mutations affecting GP(1,2) functions can alter virus growth properties. We generated a recombinant vesicular stomatitis virus encoding Ebola virus Makona variant GP(1,2) (rVSV-MAK-GP) and...
Gardado en:
| Publicado en: | J Virol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5651722/ https://ncbi.nlm.nih.gov/pubmed/28539437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00392-17 |
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