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IL-17 signalling restructures the nasal microbiome and drives dynamic changes following Streptococcus pneumoniae colonization

BACKGROUND: The bacterial pathogen Streptococcus pneumoniae colonizes the nasopharynx prior to causing disease, necessitating successful competition with the resident microflora. Cytokines of the IL-17 family are important in host defence against this pathogen but their effect on the nasopharyngeal...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Ritchie, Neil D., Ijaz, Umer Z., Evans, Tom J.
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651609/
https://ncbi.nlm.nih.gov/pubmed/29058583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4215-3
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