Curaxin CBL0100 Blocks HIV-1 Replication and Reactivation through Inhibition of Viral Transcriptional Elongation

Despite combination antiretroviral therapy (cART), acquired immunodeficiency syndrome (AIDS), predominantly caused by the human immunodeficiency virus type 1 (HIV-1), remains incurable. The barrier to a cure lies in the virus' ability to establish a latent infection in HIV/AIDS patients. Unsurp...

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Bibliografiske detaljer
Udgivet i:Front Microbiol
Main Authors: Jean, Maxime J., Hayashi, Tsuyoshi, Huang, Huachao, Brennan, Justin, Simpson, Sydney, Purmal, Andrei, Gurova, Katerina, Keefer, Michael C., Kobie, James J., Santoso, Netty G., Zhu, Jian
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651003/
https://ncbi.nlm.nih.gov/pubmed/29089933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.02007
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