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Alzheimer disease macrophages shuttle amyloid-beta from neurons to vessels, contributing to amyloid angiopathy

Neuronal accumulation of oligomeric amyloid-β (Aβ) is considered the proximal cause of neuronal demise in Alzheimer disease (AD) patients. Blood-borne macrophages might reduce Aβ stress to neurons by immigration into the brain and phagocytosis of Aβ. We tested migration and export across a blood-bra...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Acta Neuropathol
Egile Nagusiak: Zaghi, Justin, Goldenson, Ben, Inayathullah, Mohammed, Lossinsky, Albert S., Masoumi, Ava, Avagyan, Hripsime, Mahanian, Michelle, Bernas, Michael, Weinand, Martin, Rosenthal, Mark J., Espinosa-Jeffrey, Araceli, de Vellis, Jean, Teplow, David B., Fiala, Milan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650912/
https://ncbi.nlm.nih.gov/pubmed/19139910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-008-0481-0
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