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Tumor-residing Batf3 dendritic cells are required for effector T cell trafficking and adoptive T cell therapy

Effector T cells have the capability of recognizing and killing cancer cells. However, whether tumors can become immune-resistant through exclusion of effector T cells from the tumor microenvironment is not known. By using a tumor model resembling non-T cell-inflamed human tumors, we assessed whethe...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Spranger, Stefani, Dai, Daisy, Horton, Brendan, Gajewski, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650691/
https://ncbi.nlm.nih.gov/pubmed/28486109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.04.003
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