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Metformin inhibits esophageal squamous cell carcinoma-induced angiogenesis by suppressing JAK/STAT3 signaling pathway

Although it has been known that the tumor microenvironment affects angiogenesis, the precise mechanism remains unclear. In this study, we simulated the microenvironment of human esophageal squamous cell carcinoma (ESCC) by tumor conditioned medium (TCM) to assess the influence on normal endothelial...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Yang, Yi, Jin, Guoguo, Liu, Hangfan, Liu, Kangdong, Zhao, Jimin, Chen, Xinhuan, Wang, Dongyu, Bai, Ruihua, Li, Xiang, Jang, Yanan, Lu, Jing, Xing, Ying, Dong, Ziming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650371/
https://ncbi.nlm.nih.gov/pubmed/29088816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20341
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