Metformin inhibits esophageal squamous cell carcinoma-induced angiogenesis by suppressing JAK/STAT3 signaling pathway

Although it has been known that the tumor microenvironment affects angiogenesis, the precise mechanism remains unclear. In this study, we simulated the microenvironment of human esophageal squamous cell carcinoma (ESCC) by tumor conditioned medium (TCM) to assess the influence on normal endothelial...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yang, Yi, Jin, Guoguo, Liu, Hangfan, Liu, Kangdong, Zhao, Jimin, Chen, Xinhuan, Wang, Dongyu, Bai, Ruihua, Li, Xiang, Jang, Yanan, Lu, Jing, Xing, Ying, Dong, Ziming
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650371/
https://ncbi.nlm.nih.gov/pubmed/29088816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20341
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