Metformin inhibits esophageal squamous cell carcinoma-induced angiogenesis by suppressing JAK/STAT3 signaling pathway

Although it has been known that the tumor microenvironment affects angiogenesis, the precise mechanism remains unclear. In this study, we simulated the microenvironment of human esophageal squamous cell carcinoma (ESCC) by tumor conditioned medium (TCM) to assess the influence on normal endothelial...

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Udgivet i:Oncotarget
Main Authors: Yang, Yi, Jin, Guoguo, Liu, Hangfan, Liu, Kangdong, Zhao, Jimin, Chen, Xinhuan, Wang, Dongyu, Bai, Ruihua, Li, Xiang, Jang, Yanan, Lu, Jing, Xing, Ying, Dong, Ziming
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650371/
https://ncbi.nlm.nih.gov/pubmed/29088816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20341
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