ERG overexpression plus SLC45A3 (prostein) and PTEN expression loss: Strong association of the triple hit phenotype with an aggressive pathway of prostate cancer progression

TMPRSS2 and SLC45A3 rearrangements may coexist in the same tumor. ERG rearrangements and PTEN loss are concomitant events in prostate cancer (PrCa), and can cooperate in progression. We have reported that mRNA expression of TMPRSS2-ERG and SLC45A3-ERG rearrangements plus PTEN loss define an aggressi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hernández-Llodrà, Silvia, Juanpere, Nuria, de Muga, Silvia, Lorenzo, Marta, Gil, Joan, Font-Tello, Alba, Agell, Laia, Albero-González, Raquel, Segalés, Laura, Merino, José, Serrano, Laia, Fumadó, Lluís, Cecchini, Lluís, Lloreta-Trull, Josep
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650326/
https://ncbi.nlm.nih.gov/pubmed/29088771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18266
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