The shortening of leukocyte telomere length relates to DNA hypermethylation of LINE-1 in type 2 diabetes mellitus

BACKGROUND: We aim to investigate the cross-talking of leukocyte telomere length (LTL) and DNA methylation of LINE-1 in type 2 diabetes mellitus (T2DM). RESULTS: LTL (ratio of the copy number of telomere [T] repeats to that of a single [S] gene) was significantly shortened in T2DM compared with cont...

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Vydáno v:Oncotarget
Hlavní autoři: Wu, Yue, Cui, Wei, Zhang, Donghong, Wu, Wei, Yang, Zhuo
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650315/
https://ncbi.nlm.nih.gov/pubmed/29088760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18167
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