Inhibition of LSD1 epigenetically attenuates oral cancer growth and metastasis

Lysine-specific demethylase 1 (LSD1) is a nuclear histone demethylase and a member of the amine oxidase (AO) family. LSD1 is a flavin-containing AO that specifically catalyzes the demethylation of mono- and di-methylated histone H3 lysine 4 through an FAD-dependent oxidative reaction. LSD1 is inappr...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Alsaqer, Saqer F., Tashkandi, Mustafa M., Kartha, Vinay K., Yang, Ya-Ting, Alkheriji, Yazeed, Salama, Andrew, Varelas, Xaralabos, Kukuruzinska, Maria, Monti, Stefano, Bais, Manish V.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Priority Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650269/
https://ncbi.nlm.nih.gov/pubmed/29088714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19637
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