Polymorphism T81C in H-RAS Oncogene Is Associated With Disease Progression in Imatinib (TKI) Treated Chronic Myeloid Leukemia Patients

BACKGROUND: Mammalian cells contain three functional RAS proto-oncogenes, known as H-RAS, K-RAS, and N-RAS, which encode small GTP-binding proteins in terms of p21(ras)s. RAS genes have been elucidated as major participants in the development and progression of cancer. A single nucleotide polymorphi...

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Bibliografiske detaljer
Udgivet i:World J Oncol
Main Authors: Mir, Rashid, Ah, Imtiyaz, Javid, Jamsheed, Zuberi, Mariyam, Guru, Sameer, Mirza, Masroor, Farooq, Shazia, Yadav, Prasant, Ray, Prakash C., Gupta, Naresh, Saxena, Alpana
Format: Artigo
Sprog:Inglês
Udgivet: Elmer Press 2015
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649720/
https://ncbi.nlm.nih.gov/pubmed/29147425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14740/wjon912e
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