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How to normalize metatranscriptomic count data for differential expression analysis

BACKGROUND: Differential expression analysis on the basis of RNA-Seq count data has become a standard tool in transcriptomics. Several studies have shown that prior normalization of the data is crucial for a reliable detection of transcriptional differences. Until now it has not been clear whether a...

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Pubblicato in:PeerJ
Autori principali: Klingenberg, Heiner, Meinicke, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: PeerJ Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649605/
https://ncbi.nlm.nih.gov/pubmed/29062598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.3859
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