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Promises and pitfalls of immune-based strategies for Huntington's disease

Huntington's disease (HD) is an autosomal-dominant neurodegenerative disease characterized by the selective loss of neurons in the striatum and cortex, leading to progressive motor dysfunction, cognitive decline and behavioral symptoms. HD is caused by a trinucleotide (CAG) repeat expansion in...

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Detalhes bibliográficos
Publicado no:Neural Regen Res
Main Authors: Colpo, Gabriela Delevati, Stimming, Erin Furr, Rocha, Natalia Pessoa, Teixeira, Antonio Lucio
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649455/
https://ncbi.nlm.nih.gov/pubmed/29089980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.215245
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