Peripheral Leukocytosis Is Inversely Correlated with Intratumoral CD8+ T-Cell Infiltration and Associated with Worse Outcome after Chemoradiotherapy in Anal Cancer

Peripheral blood leukocytosis has been implicated in promoting tumor progression leading to worse survival, but the mechanisms behind this phenomenon remain unexplored. Here, we examined the prognostic role of pretreatment white blood cell (WBC) count and clinicopathologic parameters in the context...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Martin, Daniel, Rödel, Franz, Winkelmann, Ria, Balermpas, Panagiotis, Rödel, Claus, Fokas, Emmanouil
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649213/
https://ncbi.nlm.nih.gov/pubmed/29085358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01225
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