Liver-infiltrating CD11b(−)CD27(−) NK subsets account for NK-cell dysfunction in patients with hepatocellular carcinoma and are associated with tumor progression

Natural killer (NK) cells have a vital role in killing hepatocellular carcinoma (HCC) cells; however, the mechanism underlying tumor-infiltrating NK (TINK)-cell dysfunction remains poorly understood. Using flow cytometry staining, we precisely characterized the frequency, phenotype and function of N...

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Publicat a:Cell Mol Immunol
Autors principals: Zhang, Qiong-Fang, Yin, Wen-Wei, Xia, Yang, Yi, Ya-Yang, He, Qiu-Feng, Wang, Xing, Ren, Hong, Zhang, Da-Zhi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649104/
https://ncbi.nlm.nih.gov/pubmed/27321064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2016.28
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