Epigenetic mediated zinc finger protein 671 downregulation promotes cell proliferation and tumorigenicity in nasopharyngeal carcinoma by inhibiting cell cycle arrest

BACKGROUND: Epigenetic abnormalities play important roles in nasopharyngeal cancer (NPC), however, the epigenetic changes associated with abnormal cell proliferation remain unclear. METHODS: We detected epigenetic change of ZNF671 in NPC tissues and cell lines by bisulfite pyrosequencing. We evaluat...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Zhang, Jian, Wen, Xin, Liu, Na, Li, Ying-Qin, Tang, Xin-Ran, Wang, Ya-Qin, He, Qing-Mei, Yang, Xiao-Jing, Zhang, Pan-Pan, Ma, Jun, Sun, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649082/
https://ncbi.nlm.nih.gov/pubmed/29052525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0621-2
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