Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia

Relapse is a major problem in acute myeloid leukemia (AML) and adversely affects survival. In this phase 2 study, we investigated the effect of vaccination with dendritic cells (DCs) electroporated with Wilms’ tumor 1 (WT1) messenger RNA (mRNA) as postremission treatment in 30 patients with AML at v...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Anguille, Sébastien, Van de Velde, Ann L., Smits, Evelien L., Van Tendeloo, Viggo F., Juliusson, Gunnar, Cools, Nathalie, Nijs, Griet, Stein, Barbara, Lion, Eva, Van Driessche, Ann, Vandenbosch, Irma, Verlinden, Anke, Gadisseur, Alain P., Schroyens, Wilfried A., Muylle, Ludo, Vermeulen, Katrien, Maes, Marie-Berthe, Deiteren, Kathleen, Malfait, Ronald, Gostick, Emma, Lammens, Martin, Couttenye, Marie M., Jorens, Philippe, Goossens, Herman, Price, David A., Ladell, Kristin, Oka, Yoshihiro, Fujiki, Fumihiro, Oji, Yusuke, Sugiyama, Haruo, Berneman, Zwi N.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2017
Fag:
Immunobiology and Immunotherapy
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649080/
https://ncbi.nlm.nih.gov/pubmed/28830889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-04-780155
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