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Breathing new life into an old target: pulmonary disease drugs for Parkinson’s disease therapy

Increases in α-synuclein protein expression are suspected to increase the risk of the development of Parkinson’s disease (PD). A recent study has demonstrated that β2-adrenergic receptor (β2AR) agonists decrease histone acetylation in the α-synuclein gene and suppress transcription. Coupled with the...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Abdelmotilib, Hisham, West, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649055/
https://ncbi.nlm.nih.gov/pubmed/29052536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0483-4
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