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Negative genic switch of HER-2 in the primary tumor instead of the synchronous metastatic nodal lesions after neoadjuvant chemotherapy in a patient with primary HER2-positive breast cancer

BACKGROUND: A few retrospective studies have indicated that neoadjuvant chemotherapy (NAC) in breast cancer may change biomarker profiles of the primary tumor. Little is known about the status of HER-2 gene of the synchronous nodal metastases when that of the residual tumor undergoes negative conver...

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Detalhes bibliográficos
Publicado no:World J Surg Oncol
Main Authors: Chen, Hao-ran, Wu, Yu-tuan, Yu, Qiu-bo, Yang, Ya-ying, Wei, Yu-xian, Li, Hong-yuan, Wu, Kai-nan, Kong, Ling-quan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649047/
https://ncbi.nlm.nih.gov/pubmed/29052527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12957-017-1255-8
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