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Surface marker profiling of SH-SY5Y cells enables small molecule screens identifying BMP4 as a modulator of neuroblastoma differentiation

Neuroblastoma is the most common extra-cranial solid tumor in children. Its broad spectrum of clinical outcomes reflects the underlying inherent cellular heterogeneity. As current treatments often do not lead to tumor eradication, there is a need to better define therapy-resistant neuroblastoma and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Ferlemann, Fraua Christina, Menon, Vishal, Condurat, Alexandra Larisa, Rößler, Jochen, Pruszak, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648761/
https://ncbi.nlm.nih.gov/pubmed/29051534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13497-8
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