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Localization of TFPI-2 in the nucleus modulates MMP-2 gene expression in breast cancer cells

TFPI-2 has recently been recognized as a tumor suppressor, which not only plays a fundamental role in modulation of ECM integrity, but also involves the regulation of many oncogenes. In this study, we investigated the potential mechanism of TFPI-2 in the suppression of breast cancer growth and invas...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Wang, Guangli, Zeng, Yao, Chen, Shaoying, Li, Deling, Li, Wei, Zhou, Yanchun, Singer, Robert H., Gu, Wei
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648759/
https://ncbi.nlm.nih.gov/pubmed/29051606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14148-8
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