High-Resolution Mapping of Chromatin Conformation in Cardiac Myocytes Reveals Structural Remodeling of the Epigenome in Heart Failure

BACKGROUND: Cardiovascular disease is associated with epigenomic changes in the heart; however, the endogenous structure of cardiac myocyte chromatin has never been determined. METHODS: To investigate the mechanisms of epigenomic function in the heart, genome-wide chromatin conformation capture (Hi-...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Rosa-Garrido, Manuel, Chapski, Douglas J., Schmitt, Anthony D., Kimball, Todd H., Karbassi, Elaheh, Monte, Emma, Balderas, Enrique, Pellegrini, Matteo, Shih, Tsai-Ting, Soehalim, Elizabeth, Liem, David, Ping, Peipei, Galjart, Niels J., Ren, Shuxun, Wang, Yibin, Ren, Bing, Vondriska, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2017
Assuntos:
Original Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648689/
https://ncbi.nlm.nih.gov/pubmed/28802249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.029430
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