OncoPPi-informed discovery of Mitogen-Activated Protein Kinase Kinase 3 as a novel binding partner of c-Myc

Mitogen-activated protein kinase kinase 3 (MKK3) is a dual threonine/tyrosine protein kinase that regulates inflammation, proliferation and apoptosis through specific phosphorylation and activation of the p38 MAPK. However, the role of MKK3 beyond p38-signaling remains elusive. Recently, we reported...

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Veröffentlicht in:Oncogene
Hauptverfasser: Ivanov, Andrei A., Gonzalez-Pecchi, Valentina, Khuri, Layla F., Niu, Qiankun, Wang, Yifeng, Xu, Yiran, Bai, Yan, Mo, Xiu-Lei, Prochownik, Edward V., Johns, Margaret A., Du, Yuhong, Khuri, Fadlo R., Fu, Haian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648601/
https://ncbi.nlm.nih.gov/pubmed/28628118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.180
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