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Toxicity and Pharmacokinetic Profile for Single Dose Injection of ABY-029: A Fluorescent Anti-EGFR Synthetic Affibody Molecule for Human Use

PURPOSE: ABY-029, a synthetic Affibody peptide, Z03115-Cys, labeled with a near-infrared fluorophore, IRDye(®) 800CW, targeting epidermal growth factor receptor has been produced under Good Manufacturing Practices for an FDA approved first-in-use human study during surgical resection of glioma, as w...

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Detalhes bibliográficos
Publicado no:Mol Imaging Biol
Main Authors: Samkoe, Kimberley S., Gunn, Jason R., Marra, Kayla, Hull, Sally M., Moodie, Karen L., Feldwisch, Joachim, Strong, Theresa V., Draney, Daniel R., Hoopes, P. Jack, Roberts, David W., Paulsen, Keith, Pogue, Brian W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648591/
https://ncbi.nlm.nih.gov/pubmed/27909986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-016-1033-y
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