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Risk of severe hematologic toxicities in cancer patients treated with PARP inhibitors: a meta-analysis of randomized controlled trials

PURPOSE: Hematologic toxicities, including neutropenia, thrombocytopenia, and anemia, are major adverse effects of PARP inhibitors (PARPis), but the incidence rate and overall risk has not been systematically studied. Therefore, we conducted a meta-analysis of published clinical trials to investigat...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Zhou, Jian xin, Feng, Li jin, Zhang, Xi
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648323/
https://ncbi.nlm.nih.gov/pubmed/29075104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S147726
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