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Inhibition of early T cell cytokine production by arsenic trioxide occurs independently of Nrf2
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a stress-activated transcription factor that induces a variety of cytoprotective genes. Nrf2 also mediates immunosuppressive effects in multiple inflammatory models. Upon activation, Nrf2 dissociates from its repressor protein, Keap1, and translo...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5648109/ https://ncbi.nlm.nih.gov/pubmed/29049341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185579 |
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