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Remote Perturbations in Tertiary Contacts Trigger Lysine Ligation to the Heme Iron in Cytochrome c

Perturbations in protein structure define the mechanism of allosteric regulation and biological information transfer. In cytochrome c (cyt c), Met80 ligation to the heme iron is critical for the protein’s electron-transfer (ET) function in oxidative phosphorylation and for suppressing its peroxidase...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Gu, Jie, Shin, Dong-Woo, Pletneva, Ekaterina V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647788/
https://ncbi.nlm.nih.gov/pubmed/28474881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01187
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