Advanced glycation end products and lipopolysaccharides stimulate interleukin-6 secretion via the RAGE/TLR4-NF-κB-ROS pathways and resveratrol attenuates these inflammatory responses in mouse macrophages

Macrophages are essential for regulating the physiology of pregnancy; however, excessive inflammatory responses to macrophages, induced by infection and/or endogenous danger signals, may potentially result in complications during pregnancy. Advanced glycation end-products (AGE) and lipopolysaccharid...

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Veröffentlicht in:Exp Ther Med
Hauptverfasser: Ohtsu, Ayaka, Shibutani, Yui, Seno, Kotomi, Iwata, Hisataka, Kuwayama, Takehito, Shirasuna, Koumei
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647727/
https://ncbi.nlm.nih.gov/pubmed/29067115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5045
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