Simvastatin attenuates renal ischemia/reperfusion injury from oxidative stress via targeting Nrf2/HO-1 pathway

Ischemia-reperfusion (I/R) injury of the kidneys is commonly encountered in the clinic. The present study assessed the efficacy of simvastatin in preventing I/R-induced renal injury in a rat model and investigated the corresponding molecular mechanisms. Rats were divided into 3 groups, including a s...

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Udgivet i:Exp Ther Med
Main Authors: Zhang, Yu, Rong, Shu, Feng, Yi, Zhao, Liqun, Hong, Jiang, Wang, Ruilan, Yuan, Weijie
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647698/
https://ncbi.nlm.nih.gov/pubmed/29067120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5023
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