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Solid phase synthesis of TyrT, a thymine–tyrosine conjugate with poly(A) RNA-binding ability

The present work deals with the synthesis and characterization of a novel nucleoamino acid derivative based on a l-tyrosine moiety to which a thymine nucleobase was anchored by means of an amide bond to the N-alpha group. This derivative, denominated by us TyrT, belongs to the family of the nucleoba...

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Publicado en:RSC Adv
Main Authors: Roviello, Giovanni N., Roviello, Valentina, Autiero, Ida, Saviano, Michele
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647564/
https://ncbi.nlm.nih.gov/pubmed/29057072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ra00294c
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