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Myosin V: Chemomechanical-coupling ratchet with load-induced mechanical slip

A chemomechanical-network model for myosin V is presented on the basis of both the nucleotide-dependent binding affinity of the head to an actin filament (AF) and asymmetries and similarity relations among the chemical transitions due to an intramolecular strain of the leading and trailing heads. Th...

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Publicat a:Sci Rep
Autor principal: Sumi, Tomonari
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647391/
https://ncbi.nlm.nih.gov/pubmed/29044145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13661-0
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