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p16 Loss and E2F/cell cycle deregulation in infant posterior fossa ependymoma
BACKGROUND: Posterior fossa (PF) ependymomas (EPNs) in infants less than 1 year of age (iEPN-PF) have a poorer clinical outcome than EPNs in older children. While radiation therapy is the standard of care for the latter, it is withheld in infants to avoid neurotoxicity to immature brain. It is unkno...
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Publicado no: | Pediatr Blood Cancer |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5647247/ https://ncbi.nlm.nih.gov/pubmed/28548702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.26656 |
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