TGF-β1 affects cell-cell adhesion in the heart in an NCAM1-dependent mechanism

The contractile property of the myocardium is maintained by cell-cell junctions enabling cardiomyocytes to work as a syncytium. Alterations in cell-cell junctions are observed in heart failure, a disease characterized by the activation of Transforming Growth Factor beta 1 (TGFβ1). While TGFβ1 has be...

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Pubblicato in:J Mol Cell Cardiol
Autori principali: Ackermann, Maegen A., Petrosino, Jennifer M., Manring, Heather R., Wright, Patrick, Shettigar, Vikram, Kilic, Ahmet, Janssen, Paul M. L., Ziolo, Mark T., Accornero, Federica
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647243/
https://ncbi.nlm.nih.gov/pubmed/28870505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2017.08.015
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