Smoking is associated with hypermethylation of the APC 1A promoter in colorectal cancer: the ColoCare Study

Smoking tobacco is a known risk factor for the development of colorectal cancer, and for mortality associated with the disease. Smoking has been reported to be associated with changes in DNA methylation in blood and in lung tumour tissues, although there has been scant investigation of how epigeneti...

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Udgivet i:J Pathol
Main Authors: Barrow, Timothy M., Klett, Hagen, Toth, Reka, Böhm, Jürgen, Gigic, Biljana, Habermann, Nina, Scherer, Dominique, Schrotz-King, Petra, Skender, Stephanie, Abbenhardt-Martin, Clare, Zielske, Lin, Schneider, Martin, Ulrich, Alexis, Schirmacher, Peter, Herpel, Esther, Brenner, Hermann, Busch, Hauke, Boerries, Melanie, Ulrich, Cornelia M., Michels, Karin B.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647242/
https://ncbi.nlm.nih.gov/pubmed/28791728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4955
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