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Quantitative proteomics identifies altered O-GlcNAcylation of structural, synaptic and memory-associated proteins in Alzheimer’s disease

Protein modification by O-linked beta-N-acetylglucosamine (O-GlcNAc) is emerging as an important factor in the pathogenesis of sporadic Alzheimer’s disease, however detailed molecular characterization of this important protein posttranslational modification at proteome level has been highly challeng...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Wang, Sheng, Yang, Feng, Petyuk, Vladislav A., Shukla, Anil K., Monroe, Matthew E., Gritsenko, Marina A., Rodland, Karin D., Smith, Richard D., Qian, Wei-Jun, Gong, Cheng-Xin, Liu, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647145/
https://ncbi.nlm.nih.gov/pubmed/28657654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4929
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