MRI detects protective effects of DAPT treatment with modulation of microglia/macrophages at subacute and chronic stages following cerebral ischemia

Notch homolog 1 (Notch 1) signaling is regarded as a potential therapeutic target for modulating the inflammatory response and exhibiting neuroprotective effects in cerebral injury following stroke. N-[N-(3,5-difluorophenacetyl)-1-alanyl]-S-phenylglycine t-butylester (DAPT) efficiently inhibits acti...

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Vydáno v:Mol Med Rep
Hlavní autoři: Hao, Xiao-Zhu, Tian, Jia-Qi, Yin, Le-Kang, Zhang, Xiao-Xue, Li, Chan-Chan, Feng, Xiao-Yuan, Yao, Zhen-Wei, Jiang, Min, Yang, Yan-Mei
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647009/
https://ncbi.nlm.nih.gov/pubmed/28849053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7200
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