Production of bFGF monoclonal antibody and its inhibition of metastasis in Lewis lung carcinoma

Basic fibroblast growth factor (bFGF) and fibroblast growth factor receptor 1 (FGFR1) are associated with drug resistance in lung cancer. In the present study, mouse monoclonal antibodies (mAb) against human bFGF, targeting the binding site of bFGF with FGFR1 were produced, and the antitumor activit...

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Bibliografiske detaljer
Udgivet i:Mol Med Rep
Main Authors: Yang, Yanqing, Luo, Zhenming, Qin, Yiyang, Zhou, Yu, Gong, Longcai, Huang, Jianfang, Wang, Hong
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5646982/
https://ncbi.nlm.nih.gov/pubmed/28765892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7099
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