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Production of bFGF monoclonal antibody and its inhibition of metastasis in Lewis lung carcinoma
Basic fibroblast growth factor (bFGF) and fibroblast growth factor receptor 1 (FGFR1) are associated with drug resistance in lung cancer. In the present study, mouse monoclonal antibodies (mAb) against human bFGF, targeting the binding site of bFGF with FGFR1 were produced, and the antitumor activit...
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| Publicado no: | Mol Med Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5646982/ https://ncbi.nlm.nih.gov/pubmed/28765892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7099 |
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