Multifunctional Molecular Beacon Micelles for Intracellular mRNA Imaging and Synergistic Therapy in Multidrug-Resistant Cancer Cells

Multidrug resistance (MDR) resulting from overexpression of P-glycoprotein (Pgp) transporters increases the drug efflux and thereby limits the chemotherapeutic efficacy. It is desirable to administer both an MDR1 gene silencer and a chemotherapeutic agent in a sequential way to generate a synergisti...

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Pubblicato in:Adv Funct Mater
Autori principali: Zhang, Ruili, Gao, Shi, Wang, Zhongliang, Han, Da, Liu, Lin, Ma, Qingjie, Tan, Weihong, Tian, Jie, Chen, Xiaoyuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5646829/
https://ncbi.nlm.nih.gov/pubmed/29056886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adfm.201701027
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