Human tissue-resident memory T cells are defined by core transcriptional and functional signatures in lymphoid and mucosal sites

Tissue-resident memory T cells (TRM) in mice mediate optimal protective immunity to infection and vaccination, while in humans, the existence and properties of TRM remain unclear. Here, we use a unique human tissue resource to determine whether human tissue memory T cells comprise a distinct subset...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Kumar, Brahma V., Ma, Wenji, Miron, Michelle, Granot, Tomer, Guyer, Rebecca S., Carpenter, Dustin J., Senda, Takashi, Sun, Xiaoyun, Ho, Siu-Hong, Lerner, Harvey, Friedman, Amy L., Shen, Yufeng, Farber, Donna L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5646692/
https://ncbi.nlm.nih.gov/pubmed/28930685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.08.078
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