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Imputation of missing genotypes within LD-blocks relying on the basic coalescent and beyond: consideration of population growth and structure
BACKGROUND: Genotypes not directly measured in genetic studies are often imputed to improve statistical power and to increase mapping resolution. The accuracy of standard imputation techniques strongly depends on the similarity of linkage disequilibrium (LD) patterns in the study and reference popul...
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| Publicado no: | BMC Genomics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5646149/ https://ncbi.nlm.nih.gov/pubmed/29041903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4208-2 |
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