PAK5-mediated phosphorylation and nuclear translocation of NF-κB-p65 promotes breast cancer cell proliferation in vitro and in vivo

BACKGROUND: Abnormal proliferation is significantly associated with the promotion of malignant tumor. Growing evidence suggest that the signal pathways of p21(cdc42/rac1)-activated kinase 5 (PAK5) have been found in various tumor progression, however, the role of PAK5 in breast cancer remains largel...

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Detalles Bibliográficos
Publicado en:J Exp Clin Cancer Res
Main Authors: Zhang, Ying-Chun, Huo, Fu-Chun, Wei, Lu-Lu, Gong, Chan-Chan, Pan, Yao-Jie, Mou, Jie, Pei, Dong-Sheng
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645986/
https://ncbi.nlm.nih.gov/pubmed/29041983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0610-5
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