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Assessing biological and technological variability in protein levels measured in pre-diagnostic plasma samples of women with breast cancer

BACKGROUND: Quantitative proteomics allows for the discovery and functional investigation of blood-based pre-diagnostic biomarkers for early cancer detection. However, a major limitation of proteomic investigations in biomarker studies remains the biological and technical variability in the analysis...

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Pubblicato in:Biomark Res
Autori principali: Yeh, Christine Y., Adusumilli, Ravali, Kullolli, Majlinda, Mallick, Parag, John, Esther M., Pitteri, Sharon J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645980/
https://ncbi.nlm.nih.gov/pubmed/29075496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-017-0110-y
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