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Human umbilical cord Wharton jelly cells promote extra-pancreatic insulin formation and repair of renal damage in STZ-induced diabetic mice

BACKGROUND: We evaluated the therapeutic effect and fate of high doses of human umbilical cord Wharton jelly cells (hUCWJCs) after IP administration to streptozotocin (STZ)-induced diabetic mice. METHODS: Type 1 diabetes (T1D) was induced in Kunming mice via IP injection of STZ. hUCWJCs were labeled...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Maldonado, Martin, Huang, Tianhua, Yang, Lujun, Xu, Lan, Ma, Lian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645864/
https://ncbi.nlm.nih.gov/pubmed/29041943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-017-0199-5
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