Glutamate in Pediatric Obsessive-Compulsive Disorder and Response to Cognitive-Behavioral Therapy: Randomized Clinical Trial

Cognitive-behavioral therapy (CBT) is effective for pediatric obsessive-compulsive disorder (OCD), but non-response is common. Brain glutamate (Glu) signaling may contribute to OCD pathophysiology and moderate CBT outcomes. We assessed whether Glu measured with magnetic resonance spectroscopy (MRS)...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: O'Neill, Joseph, Piacentini, John, Chang, Susanna, Ly, Ronald, Lai, Tsz M, Armstrong, Casey C, Bergman, Lindsey, Rozenman, Michelle, Peris, Tara, Vreeland, Allison, Mudgway, Ross, Levitt, Jennifer G, Salamon, Noriko, Posse, Stefan, Hellemann, Gerhard S, Alger, Jeffry R, McCracken, James T, Nurmi, Erika L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645751/
https://ncbi.nlm.nih.gov/pubmed/28409563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.77
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